Outline
The quality of lipids in a lipid nanoparticle (LNP) assembly is critically important to the functionality of mRNA-based therapeutics. Any unwanted chemical reaction between the lipids and the labile mRNA will affect the product stability and efficacy of the vaccine or therapeutic. In this webinar, our expert describes Evonik’s approach to superior quality control lipid analytics. In two case studies, this webinar outlines the role of novel multivariate models in speeding up timelines and increasing knowledge, and demonstrates that Evonik lipids show a consistently negligible level of N-oxide and aldehyde impurities, enabling safe usage in LNPs.
The quality of lipids in a lipid nanoparticle (LNP) assembly is critically important to the functionality of mRNA-based therapeutics. Any unwanted chemical reaction between the lipids and the labile mRNA will affect the product stability and efficacy of the vaccine or therapeutic. In this webinar, our expert describes Evonik’s approach to superior quality control lipid analytics. In two case studies, this webinar outlines the role of novel multivariate models in speeding up timelines and increasing knowledge, and demonstrates that Evonik lipids show a consistently negligible level of N-oxide and aldehyde impurities, enabling safe usage in LNPs.
