eBook: An Introduction to PLG Polymers for Long‑Acting Drug Delivery

Bioabsorbable poly(lactide-co‑glycolide) (PLG) polymers and poly(lactic acid-co-glycolic acid) (PLGA) have become an essential part of modern healthcare. Over the past five decades, these polymers have transformed how medicines are delivered – enabling long-acting injectables, implants, and localized drug‑delivery products that improve patient adherence, reduce dosing frequency, and help clinicians achieve more consistent therapeutic outcomes.

What's in it for you?

This eBook provides a comprehensive guide to understanding PLG polymers as both materials and their use in drug-delivery platforms. It traces their scientific origins, explains how polymer chemistry influences clinical performance, and outlines how commercial dosage forms are developed and manufactured. It also explores current innovation trends – from ocular and joint-specific delivery technologies to the emerging role of PLG in advanced modalities such as nanoparticles and personalized medicine.

Whether you are new to the field or looking to deepen your technical knowledge, the chapters are structured to build insight step by step, from polymer science fundamentals to product design and outlook.

  • The scientific foundations and history of bioabsorbable PLG polymers
  • How polymer chemistry, molecular weight, end‑group chemistry, and microstructure influence drug‑release performance
  • Key considerations when matching PLG polymers with drug properties and target product profiles
  • An overview of commercial manufacturing approaches for microparticles, implants, and in situ forming depots
  • Current innovation trends, including ocular delivery, intra‑articular therapies, and emerging nanoparticle applications


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