The quality of lipids in a lipid nanoparticle assembly is critically important to the functionality of mRNA-based therapeutics. Any unwanted chemical reaction between lipids and the labile mRNA will affect the product stability and efficacy of a vaccine or therapeutic. The findings of our recent study demonstrate that Evonik is capable of manufacturing high-quality lipids with a purity greater than 99% and a consistently low level of the N-Oxide impurity.
